RESEARCH INTERESTS
1. Coordination Supramolecular Chemistry: We aim to conduct in-depth research on the precise and efficient construction of multi-level chiral coordination supramolecular frameworks. Our focus encompasses the investigation of mechanisms and rules governing chirality, as well as chiral transfer, amplification, and regulation. This research endeavor holds the potential to provide effective methods and inspiration for developing innovative chiral functional supramolecular assemblies and materials.
2. Organometallic Catalysis: We are dedicated to the efficient synthesis of novel chiral ligands and organometallic catalysts. Our focus includes uncovering the impact of various factors, such as the chiral ligand framework, coordinating atoms, non-covalent interactions, metal oxidation states, spin states, and confined environments, on catalyst performance. This may help to provide insights and methods for the preparation of highly active and cost-effective chiral organometallic catalysts.
EDUCATION AND ACADEMIC CAREER
2024每now Professor, College of Chemistry, Sichuan University (SCU)
2023每2023 Walter Benjamin Postdoctoral Fellowship, Fakult?t f邦r Chemie und Chemische Biologie
Anorganische Chemie, Technische Universit?t Dortmund, Supervisor: Prof. Guido Clever
2019每2023 Walter Benjamin Postdoctoral Fellowship, Yusuf Hamied Department of Chemistry, University of Cambridge, Supervisor: Prof. Jonathan Nitschke
2015每2019 PhD, Institut f邦r Chemie, Technische Universit?t Berlin, Supervisor: Prof. Martin Oestreich
2012每1015 M.S., Department of Chemistry, Shanghai University, Supervisor: Prof. Hegui Gong
2008每2012 B.S., College of Chemistry and Molecular Sciences, Henan University, Supervisor: Prof. Feng Shi
LIST OF PUBLICATIONS
1. W. Xue, L. Pesce, B. Adinarayana, T. K. Ronson, K. Wu, D. Zhang, N. Vanthuyne, T. Brotin, A. Martinez, G. M. Pavan, J. R. Nitschke. Subtle Stereochemical Effects Influence Binding and Purification Abilities of an FeII4L4 Cage. J. Am. Chem. Soc. 2023, 145, 5570每5575.
2. W. Xue, K. Wu, N. Ouyang, T. Brotin, J. R. Nitschke. Allosterically Regulated Guest Binding Determines Framework Symmetry for an FeII4L4 Cage. Angew. Chem. Int. Ed. 2023, 62, e202301319.
3. W. Xue, T. K. Ronson, Z. Lu, J. R. Nitschke. Solvent Drives Switching between 托 and 忖 Metal Center Stereochemistry of M8L6 Cubic Cages. J. Am. Chem. Soc. 2022, 144, 6136每6142.
4. W. Xue,* X. Jia, X. Wang, X. Tao, Z. Yin, H. Gong*. Nickel-Catalyzed Formation of Quaternary Carbon Centers Using Tertiary Alkyl Electrophiles. Chem. Soc. Rev. 2021, 50, 4162每4184.
5. W. Xue, M. Oestreich. Beyond Carbon: Enantioselective and Enantiospecific Reactions with Catalytically Generated Boryl- and Silylcopper Intermediates. ACS Cent. Sci. 2020, 6, 1070每1081.
6. W. Xue,? W. Mao,? L, Zhang, M. Oestreich. Mechanistic Dichotomy of Magnesium- and Zinc-Based Germanium Nucleophiles in the C(sp3)每Ge Cross-Coupling with Alkyl Electrophiles. Angew. Chem. Int. Ed. 2019, 58, 6440每6443.
7. W. Mao,? W. Xue,? E. Irran, M. Oestreich. Copper-Catalyzed Regio- and Enantioselective Addition of Silicon Grignard Reagents to Alkenes Activated by Azaaryl Groups. Angew. Chem. Int. Ed. 2019, 58, 10723每10726. (Highlighted as Hot Paper; Synfacts 2019, 15, 1024).
8. W. Xue, R. Shishido, M. Oestreich. Bench-Stable Stock Solutions of Silicon Grignard Reagents: Application to Iron- and Cobalt-Catalyzed Radical C(sp3)每Si Cross-Coupling Reactions. Angew. Chem. Int. Ed. 2018, 57, 12141每12145. (Highlighted as VIP Paper; Synfacts 2018, 14, 1174; Org. Process Res. Dev. 2018, 22 ,1687)
9. W. Xue, M. Oestreich. Copper-Catalyzed Decarboxylative Radical Silylation of Redox-Active Aliphatic Carboxylic Acid Derivatives. Angew. Chem. Int. Ed. 2017, 56, 11649每11652.
10. W. Xue, Z.-W. Qu. S. Grimme, M. Oestreich. Copper-Catalyzed Cross-Coupling of Silicon Pronucleophiles with Unactivated Alkyl Electrophiles Coupled with Radical Cyclization. J. Am. Chem. Soc. 2016, 138, 14222每14225.
11. W. Xue, M. Oestreich. Silicon Grignard Reagents as Nucleophiles in Transition-Metal-Catalyzed Allylic Substitution. Synthesis 2019, 51, 233每239.
12. W. Xue,? H. Xu,? Z. Liang, H. Gong. Nickel-Catalyzed Reductive Cyclization of Alkyl Dihalides.Org. Lett. 2014, 16, 4984每4987. (Highlighted by Synfacts, 2015, 11, 0076)
13. Z. Liang,? W. Xue,? K. Lin, H. Gong. Nickel-Catalyzed Reductive Reductive Methylation of Alkyl Halides and Acid Chlorides with Methyl p-Tosylate. Org. Lett. 2014, 16, 5620每5623.
14. Z. Zhao, Y. Gong, W. Tong, W. Xue*, H. Gong.* Ni-Catalyzed Cross-Electrophile Coupling of Aryl Triflates withThiocarbonates via C每O/C每O Bond Cleavage. Org. Lett. 2021, 23,2158每2163.
15. X. Tao, K. Yao,* W. Xue.* Ni-Catalyzed Cross-Electrophile Coupling of 汐-Hydroxy Carbonyl Compound-Derived Oxalates with Vinyl Triflates. Tetrahedron Lett. 2021, 73, 153129.
16. H. Zhu, L. Pesce, R. Chowdhury, W. Xue, K. Wu, T. K. Ronson, R. H. Friend, G. M. Pavan, J. R. Nitschke. Stereocontrolled Self-Assembly of a Helicate-Bridged CuI12L4 Cage That Emits Circularly Polarized Light. J. Am. Chem. Soc. 2024, 10.1021/jacs.3c11321.
17. K. Wu, T. K. Ronson, L. Goh, W. Xue, A. W. Heard, P. Su, X. Li, M. Vinkovic?, J. R. Nitschke. A Diverse Array of Large Capsules Transform in Response to Stimuli. J. Am. Chem. Soc. 2023, 145, 11356每11363
18. S. B?hr, W. Xue, M. Oestreich. C(sp3)每Si Cross-Coupling. ACS Catal. 2019, 9, 16每24.
19. M. Zheng, W. Xue, T. Xue, H. Gong. Ester Formation via Nickel-Catalyzed Reductive Coupling of Alkyl Halides with Chloroformates. Org. Lett. 2016, 18, 6152每6155.
20. X. Wang, S. Wang, W. Xue, H. Gong. Nickel-Catalyzed Reductive Coupling of Aryl Bromides withTertiary Alkyl Halides. J. Am. Chem. Soc. 2015, 137, 11562每11565.
21. J. Gu, X. Wang, W. Xue, H. Gong. Nickel-Catalyzed Reductive Coupling of Alkyl Halides with Other Electrophiles: Concept and Mechanistic Considerations. Org. Chem. Front. 2015, 2, 1411每1421. (ESI Highly Cited Paper)
22. P. Li, C. Wu, J. Zhao, Y. Li, W. Xue, F. Shi. One-Pot Synthesis of Dihydrobenzisoxazoles from Hydroxylamines, Acetylenedicarboxylates, and Arynes via in situ Generation of Nitrones. Can. J. Chem. 2013, 91, 43每50.
23. C. Wu, P. Li, Y, Fang, J, Zhao, W. Xue, Y. Li, R. C. Larock, F. Shi. Pd-Catalyzed Oxidative Coupling of Monosubstituted Sydnones and Terminal Alkynes. Tetrahedron Lett. 2011, 52, 3797每3801.
